Schizophrenia and Psychotic Disorders

 


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1. The following concepts are matched correctly with the person that proposed the idea:  
A. Greisinger - ‘unitary psychosis’
T
B. Kraepelin - ‘dementia praecox’
T
C. Bleuler - ‘praecox feeling’
F
D. Langfeldt - ‘systemic schizophrenia’
F
E. Carpenter - ‘deficit syndrome’
T
   
2. The following are Schneiderian 1st Rank symptoms:  
A. Thought echo
T
B. Ideas of reference
F
C. Somatic hallucinations
T
D. Delusional mood
F
E. Flatness of affect
F
   
3. Regarding the epidemiology and associations of schizophrenia:  
A. Increased rate in Sweden
T
B. Increased rate in US Hutterites
F
C. Association with brain injury
T
D. The positive association with rheumatoid arthritis suggests an immunological basis
F
E. Increased incidence in Afro-Caribbean migrants to the UK
T
   
4. In schizophrenia:  
A. The risk of bipolar illness is increased in 1st degree relatives of schizophrenic patients
F
B. The risk of schizophrenia is increased in 1st degree relatives of patients with schizoaffective disorder
T
C. Although eye-movement abnormalities are found in relatives of schizophrenics, evoked potentials are normal
F
D. There is a 10 % risk of schizophrenia in siblings of affected individuals
T
E. There is a 25 % risk of schizophrenia in children of affected parents
F
   
5. Regarding the aetiology of schizophrenia:  
A. The brains of twins discordant for schizophrenia are normal, indicating that brain abnormalities are a significant aetiological factor
F
B. Chromosome 5 has been implicated
T
C. The D4 dopamine receptor gene is located on chromosome 5
F
D. Patients born in winter have an increased risk for the disorder
T
E. Exposure to the influenza virus in the 1st trimester has been implicated
F
   
6. Regarding the aetiology of schizophrenia:  
A. Higher incidence in men
F
B. Men develop the illness 8-10 years before women
F
C. Fertility rates among schizophrenic patients are reduced by 25 %
T
D. Increased prevalence in urban settings, particularly among females
F
E. The ‘Breeder Hypothesis’ was proposed by Farris and Dunham
T
   
7. The following statements are about aetiological concepts:  
A. Social drift hypothesis suggests that stresses related to deprived areas increase the risk for schizophrenia
F
B. Bateson (1956) implicated the role of the ‘schizophrenogenic mother’
F
C. Lidz (1957) developed ‘Family Schism Theory’
T
D. Schizophrenics have more life events in the 6 weeks preceding relapse or admission
F
E. Life events tend to be clustered in the 3 weeks preceding admission
T
   
8. The following statements relate to findings in schizophrenia:  
A. The brains of schizophrenics are 6 % lighter and 4 % smaller than normal controls
T
B. There is a reduced number of neurones in the temporal lobes
T
C. Increased disorganization of neurones in the hippocampus
T
D. Schizophrenic patients tend to have enlarged 3rd ventricles
T
E. Enlarged lateral ventricles are correlated with good response to treatment
F
   
9. Regarding brain changes in Schizophrenia:  
A. Changes are less evident in the left side of the brain
F
B. The syndrome of ‘reality distortion’ is associated with decreased blood flow in the left parahippocampal gyrus
F
C. Psychomotor poverty is associated with increased blood flow in the caudate nuclei
T
D. ‘Disorganization’ is associated with decreased blood flow in the right prefrontal cortex, and the right anterior cingulate
F
E. EEGs show decreased theta activity, especially in the acute illness
F
   
10. Biochemical changes found in schizophrenia include:  
A. Dopamine receptor supersensitivity following antipsychotic treatment
T
B. Dopamine underactivity in the mesolimbic pathways may be responsible for schizophrenia
F
C. Reduced GABA receptors in the temporal lobe
T
D. Increased GABA receptors in the orbitofrontal cortex
T
E. Abnormal cholecystokinin (CCK) function
T
   
11. Neuropsychological abnormalities include:  
A. Defects in verbal learning and memory
T
B. The Wisconsin Card Sorting Test shows no abnormality in schizophrenic patients
F
C. Impaired short term memory
F
D. Normal long term memory
F
E. Impairment of verbal memory and learning suggests left temporal-hippocampal involvement
T
   
12. Predictors of good outcome in schizophrenia include:  
A. Florid psychotic presentation
T
B. Prominent affective symptoms
T
C. Acute onset
T
D. Older age at onset
F
E. Long initial episode
F
   
13. In schizophrenia:  
A. Less than 5 % of suicides are by schizophrenic patients
F
B. Suicide usually occurs in the late stages of the illness
F
C. Illness course may plateau after the first 5 years
T
D. Overall mortality (removing the increased risk of suicide) is normal
F
E. More benign course in developing countries
T
   
14. Regarding the treatment of schizophrenia:  
A. Low dose neuroleptics are as effective as other regimes
F
B. 5 % of patients are treatment-resistant
F
C. Clozapine is a second line drug for treatment-resistant schizophrenia
F
D. ECT can be useful in catatonic, or depressive states
T
E. Psychosocial treatments are of little benefit
F
   
15. The following are true of schizoaffective disorder:  
A. It was first described by Kasanin
T
B. Schizodepressive subtypes are more related to schizophrenia
T
C. Schizomanic subtypes are more related to affective disorders
T
D. Schizophrenic symptoms are associated with a good outcome
F
E. Schizomanic patients have an episodic course, with a poorer outcome
F
   
16. The following are recognized associations with delusional jealousy:  
A. Depression
T
B. Alcoholism
T
C. Impotence
F
D. Personality disorder
T
E. Pervasive sense of inadequacy
T


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